Science Highlights
A bi-annual summary of projects conducted and supported by PSC computational resources, educational programs, and staff expertise
Rapid ID of Potential Anti-COVID-19 Agents Powered by Bridges-AI
AI Identifies More Than 20,000 Compounds with Possible Anti-Virus Activity, Thousands of Times Faster than Earlier Methods
CRISPR Simulation Points to Improved DNA Editing, Gene Therapy
Virtual Cas9 Protein on Anton 2 at PSC Aids Search for Cures for Genetic Diseases
AI Makes Deluge of Fast Radio Burst Data Manageable
Artificial Intelligence on Bridges Makes Processing Thousands of Fast Radio Burst Candidates Possible by Human Experts
Two New PSC Systems Begin Operations
Two New PSC Systems Begin Operations Bridges-2 Supercomputing Platform Begins Operations at PSC A $10-million grant from the National Science Foundation (NSF) has funded a new major supercomputing platform at PSC. In partnership with Hewlett Packard Enterprise...
Answering the Call
PSC Answers the Call PSC Systems Support Urgent COVID-19 Science With the nation—and the world—disrupted by the COVID-19 pandemic, PSC is answering the call to action. The center has given the national research community expedited access to its systems Bridges;...
Star Crash
Star Crash(es) Bridges Powers Artificial Intelligence that Can Speed Simulations of Neutron Star Mergers and Repeated Simulations that Predict Unique Signal from Unequal Mergers Collisions between neutron stars involve some of the most extreme physics in the Universe....
Doubling Down
Computation with Bridges Points to Unexpected Mechanism for DNA Duplication in Parkinson’s Disease The progressive disability of Parkinson’s disease carries a heavy toll both in numbers—nearly a million people in the U.S. have it—and in suffering. The wrong number...
Off to a Good Start
Off to a Good Start Anton 2 Simulations Kick off Drug Safety Prediction Pipeline Many possibly useful drugs are abandoned because they increase the QT interval of the heartbeat. This is because QT prolongation can cause life-threatening side effects. But not all...
Every Calculation Stabs
Every Calculation Stabs Combination of Bridges and Anton 2 Allows Team to Span Time Scales in Simulating Dagger-Like Microbe-Killing Molecule Medical science is in a race to develop new and better antimicrobial agents to address infection and other human diseases. One...
Experimental Introduction
Introducing Experimental Data into Molecular Simulations on Bridges Improves Predictions of Metallic Glass Structure Metallic glass has great strength and flexibility and can be engineered for specific uses. These properties make it useful for medical devices,...
