Finding the Balance

Pitt Researchers Use Bridges to OptimizeDoctor Visitsfor Kidney Patients

The biggest causes of death in developed countries—heart disease, cancer, chronic organ failure—are complex conditions that may be best treated by long-term management rather than attempting to “cure” them. Researchers at the University of Pittsburgh have used the Bridges supercomputer at the Pittsburgh Supercomputing Center to mine a massive database of medical records to optimize preventive doctor visits for individual patients with chronic kidney disease.

Read more: Finding the Balance

Snapping into Place

Anton 2 Simulations Give Clue to Poorly Understood Role of Cellular “Bricks”

Tubulin proteins are the cell’s “Lego bricks,”connecting with themselves into tubular structures that help give living cells shape and stiffness. But the protein may also play a role in energy generation by the cell’s mitochondria, with individual tubulin “bricks” sticking to the surface of mitochondria by a poorly understood mechanism. Scientists at the National Institute of Standards and Technology and elsewhere used the Anton 2 system hosted at PSC to unravel how tubulin snaps into place—offering clues to phenomena as different as chemotherapy side effects, cancer, and brain development.

Read more: Snapping into Place

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Featured Projects

Data Exacell (DXC)

DXC

The Data Exacell (DXC) is a research pilot project to create, deploy, and test software and hardware building blocks to enable data analytics in scientific research.

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PSC is a service provider of the Extreme Science and Engineering Discovery Environment (XSEDE).