The Best Thing Since Sliced Bread?

Zebrafish Study Reveals First Fine Structure of a Complete Vertabrate Brain

Why It's Important

Every thought, every feeling, every sensation—and every behavioral illness—ultimately depends on how our brains work. Despite decades of stunning advances in imaging the brain and measuring its activity, though, we still don’t understand how even a simple vertebrate brain works.

Read more: The Best Thing Since...

Identifying Cancer DNA Changes with XSEDE/PSC Resources

The scientific field of bioinformatics has for the past five years relied on increasingly larger data sets for new and innovative research. With few in the field trained in computer science, many groups, like the University of Pittsburgh Cancer Institute, have turned to XSEDE for help. Read More

HOOKED UP

A common way for proteins to hold themselves together is with disulfide bridges. But scientists don’t completely understand why some proteins need them to “hook up” their structure. Researchers used the DESRES Anton system hosted at PSC to discover the critical role disulfides play in holding together MCoTI-II, a natural pesticide that would fall apart without disulfide bridges.

Read more: Hooked Up

Bridges & CMU Take AI Research to the Next Level

GUT CHECK

While diabetes poses many life- and limb-threatening problems, it also causes serious changes and problems in the digestive tract. A study using PSC’s Bridges system sifted through the DNA of thousands of microbe species in the healthy and diabetic intestines to learn how to help reduce digestive symptoms—and maybe even slow the course of the disease.

Read more: GUT CHECK

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Featured Projects

Data Exacell (DXC)

DXC

The Data Exacell (DXC) is a research pilot project to create, deploy, and test software and hardware building blocks to enable data analytics in scientific research.

XSEDE Service Provider

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PSC is a service provider of the Extreme Science and Engineering Discovery Environment (XSEDE).