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Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

by Ken Chiacchia | Jul 31, 2024 | Anton, Anton 2, Research, Science Highlights

Scientists used the second-generation DESRES Anton supercomputer hosted at PSC to show how a critical protein for furture gene therapy pauses before completing its cutting of a target DNA. Credit: Aakash Saha Understanding Unexpected Motion of Protein Will Be Crucial...
Anton 2 Simulations Explain Mechanism for Loading DNA into Virus

Anton 2 Simulations Explain Mechanism for Loading DNA into Virus

by Ken Chiacchia | Sep 27, 2021 | Anton, Anton 2, Science Highlights

Anton 2 Simulations Explain mechanism for Loading DNA into Virus   Two-phase Motor Packages DNA into Viral Capsids, May Offer Drug Target To cause disease, viruses must package their DNA into new virus particles to infect more cells. An important step—and...

Protein Research Leaps Forward with Anton at Pittsburgh Supercomputing Center

by Ken Chiacchia | Jul 21, 2011 | 2011Press, Anton, Anton 2, Science Highlights

Protein Research Leaps Forward with Anton at Pittsburgh Supercomputing Center Special-purpose supercomputer’s stay is extended, with new round of time allocations PITTSBURGH, July 21, 2011 — Using a special-purpose supercomputer for biomolecular simulation, U.S....
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