by Ken Chiacchia | Apr 7, 2025 | Anton, Anton 2, Science Highlights
Adobe Stock 508244320 “Tucking In” of Viral Capsid Protein Allows Passage of Giant Structure through Nuclear Pore, Allowing Virus to Take Over The hepatitis B virus causes about 800,000 deaths per year, on par with HIV and the malaria parasite. However, as it spreads,...
by Ken Chiacchia | Jan 3, 2025 | Anton, Science Highlights
Generated models of the AT1 receptors taken from Supporting Information: Structural Rearrangement of the AT1 Receptor Modulated by Membrane Thickness and Tension, Figure S11. G Protein-Coupled Receptor Triggered by Mechanical Tension as Well as Chemical Signals,...
by Ken Chiacchia | Oct 22, 2024 | Anton, Anton 2, Research, Science Highlights
With Alzheimer’s disease, amyloid peptides combine to form fibrils, in turn forming plaques around neurons. Adobe Stock 421239213 Unexpected Way for Amyloid Peptides to Join Fibrils Explains Time Lag, then Accelerated Growth, in Fibril Formation and Disease...
by Ken Chiacchia | Aug 5, 2024 | Anton, Anton 3, COVID-19, News, Press release, Resources, Systems
Designed and Built by D. E. Shaw Research, System Will Simulate Biomolecules Roughly 100 Times Faster than General-Purpose Supercomputers A third-generation Anton supercomputer (Anton 3), developed by D. E. Shaw Research (DESRES), will soon arrive at the Pittsburgh...
by Ken Chiacchia | Jul 31, 2024 | Anton, Anton 2, Research, Science Highlights
Scientists used the second-generation DESRES Anton supercomputer hosted at PSC to show how a critical protein for furture gene therapy pauses before completing its cutting of a target DNA. Credit: Aakash Saha Understanding Unexpected Motion of Protein Will Be Crucial...
by Ken Chiacchia | Sep 27, 2021 | Anton, Anton 2, Science Highlights
Anton 2 Simulations Explain mechanism for Loading DNA into Virus Two-phase Motor Packages DNA into Viral Capsids, May Offer Drug Target To cause disease, viruses must package their DNA into new virus particles to infect more cells. An important step—and...
