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Anton Simulations Reveal How Alzheimer’s Fibril Growth May Accelerate

Anton Simulations Reveal How Alzheimer’s Fibril Growth May Accelerate

by Ken Chiacchia | Oct 22, 2024 | Anton, Anton 2, Research, Science Highlights

With Alzheimer’s disease, amyloid peptides combine to form fibrils, in turn forming plaques around neurons. Adobe Stock 421239213 Unexpected Way for Amyloid Peptides to Join Fibrils Explains Time Lag, then Accelerated Growth, in Fibril Formation and Disease...
Bridges-2 Simulations Uncover Better Ways to Inject Monoclonal Antibody Drugs

Bridges-2 Simulations Uncover Better Ways to Inject Monoclonal Antibody Drugs

by Ken Chiacchia | Oct 7, 2024 | Bridges-2, Research, Science Highlights

Understanding the movement of monoclonal antibodies through tissues can give a better picture of how to improve autoinjectors. Adobe Stock 350554958 Detailed Model of Movement of Antibodies through Tissues Reveals Ways to Improve Autoinjectors Monoclonal antibodies...
ByteBoost Workshop: Accelerating HPC Skills and Advancing Computational Research

ByteBoost Workshop: Accelerating HPC Skills and Advancing Computational Research

by Ken Chiacchia | Sep 27, 2024 | AI, Features, Neocortex, Neocortex events, Research, Science Highlights, Training

ByteBoost students and PSC staff listen as Derek Simmel, Senior Information Security Officer, gives a tour of the PSC Machine Room. Student Projects Tackle Challenges in Drug Discovery, Congressional Policy, Coordinating Heavy Air Traffic, and More Students from...
Dune Software Helps Scientists Identify Roles of Individual Cells

Dune Software Helps Scientists Identify Roles of Individual Cells

by Ken Chiacchia | Aug 28, 2024 | Bridges-2, Research, Science Highlights

A microscopic view of the large intestine, and the many different cells that comprise it. Source: AdobeStock_316295145 By Optimizing Cell Classification, the New Tool Running on Bridges-2 Promises Better Understanding of How Individual Cells Help Organs and Tissues...
Spatial Relationships Help AI Learn Without Human Help

Spatial Relationships Help AI Learn Without Human Help

by Ken Chiacchia | Aug 14, 2024 | AI, Bridges-2, Research, Science Highlights

A 3D model of a sitting area. Environmental spatial similarity could help an AI recognize the objects in a setting like this more easily. Adobe Stock: 371561612 Environmental Spatial Similarity Approach with Bridges-2 Improves Speed and Accuracy for More Flexible...
Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

Anton Simulations Explain Delay in CRISPR-Cas12a’s DNA-Cutting Function

by Ken Chiacchia | Jul 31, 2024 | Anton, Anton 2, Research, Science Highlights

Scientists used the second-generation DESRES Anton supercomputer hosted at PSC to show how a critical protein for furture gene therapy pauses before completing its cutting of a target DNA. Credit: Aakash Saha Understanding Unexpected Motion of Protein Will Be Crucial...
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