Computational Modules in Science Teaching (CMIST) brings innovative science tutorials into secondary school classrooms, focusing on integrative computational biology, physiology, and biophysics. CMIST modules include high quality, realistic 3-D animations produced with cutting-edge simulation and visualization software.
CMIST subject material is chosen to highlight critical concepts that are difficult to convey with static textbook images and words; for example, cellular transport of molecules by diffusion and osmosis, or the structure and function of enzymes in cells. Specific modules are introduced in two-hour workshops throughout the school year.  
3-D Animations

An Introduction to Enzymes

Enzyme Kinetics

The Effect of Temperature on Enzyme Catalysis



Principles of Diffusion and Molecular Flux

Diffusion Time and Distance: Cellular vs. Desktop Diffusion

Diffusion Time and Distance: Glucose Molecules vs. Sodium Ions

Brownian Motion in Water

Big Numbers in Small Spaces



Osmosis and its Effects on Red Blood Cell Volume

Osmosis: Osmotic vs. Hydrostatic Pressure



Neuromuscular Transmission and slow Channel Congental Myasthenic Syndrome

Neuromuscular Junction 1

3D Reconstruction of Nerve-Muscle Synapse

24 Active Zones



Birth of a Protein

Lotka-Volterra Reaction

Single Channel


CMIST is a program of the Biomedical Applications Group at Pittsburgh Supercomputing Center.