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Bridges-2 and AI Analysis Identify DNA Sequences Carrying Risk of Childhood Sudden Death

Bridges-2 and AI Analysis Identify DNA Sequences Carrying Risk of Childhood Sudden Death

by Ken Chiacchia | Mar 19, 2025 | Bridges-2, Science Highlights

Adobe Stock 270629805 Number and Type of Mutations Relate to Risk of Death at Earlier Age, Suggesting Focus for Future Detection and Prevention Sudden death in children is rare but devastating. A team led from Northwestern University used PSC’s flagship Bridges-2...
Human BioMolecular Atlas Program: Scientists Announce New Version of 3D Human Reference Atlas (HRA)

Human BioMolecular Atlas Program: Scientists Announce New Version of 3D Human Reference Atlas (HRA)

by Ken Chiacchia | Mar 14, 2025 | HuBMAP, News, Press release, Research, Resources

Paper in Nature Methods Charts Latest Progress, Use of HRA for Studying Human Body Across Scales Coverage and Quality of the Human Reference Atlas (HRA): Experts from many fields of science around the globe have constructed and use the HRA; the HRA Dashboard shows the...
Simulations on Bridges-2 Teach AI Program to Prevent Buckling or Breaks in Railways

Simulations on Bridges-2 Teach AI Program to Prevent Buckling or Breaks in Railways

by Ken Chiacchia | Mar 5, 2025 | Bridges-2, Science Highlights

Adobe Stock 138718634 AI Tool Would Enable Industry to Predict Temperatures that Require Maintenance or Repair, Improving Safety and Making Repairs Less Expensive Continuously welded rails were a cost game-changer in the railway industry, which contributes over $27...
HIV Protein Switch May Help Virus Squeeze into Host Cell Nucleus

HIV Protein Switch May Help Virus Squeeze into Host Cell Nucleus

by Ken Chiacchia | Feb 21, 2025 | Bridges-2, Science Highlights

The pointed end of HIV’s outer viral shell, its capsid, helps it squeeze into host cells’ nuclear pore. A team from Pitt has simulated the virus in PSC’s Bridges-2 to show how a twist in a critical protein may help it shoehorn in. Based on a figure from Yang DT et al....
Large-Scale Evolution Simulations on PSC’s Neocortex Tackle Questions about Hypermutator Evolution

Large-Scale Evolution Simulations on PSC’s Neocortex Tackle Questions about Hypermutator Evolution

by Ken Chiacchia | Feb 5, 2025 | Neocortex, Science Highlights

In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan used simulations on PSC’s Neocortex to find out why beneficial mutants rarely come to dominate real...
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