Pittsburgh Supercomputing Center 

Advancing the state-of-the-art in high-performance computing,
communications and data analytics.

Nicholas A. (Nick) Nystrom, PhDNick Nystrom

Director, Strategic Applications, Pittsburgh Supercomputing Center
Research Physicist, Dept. of Physics, Carnegie Mellon University

e-mail: nystrom@psc.edu
   
phone:   412-268-4960
mail:   PSC
300 South Craig St.
Pittsburgh, PA 15213

I run PSC's Strategic Applications Group, which develops hardware and software architectures to enable groundbreaking research, engages in research and collaborations across diverse disciplines, and facilitates researchers' early use of PSC's newest, most advanced resources.

Research Interests

Data analytics, Big Data, causal modeling, graph algorithms, genomics, machine learning (in particular, deep learning), extreme scalability, hardware and software architecture, software engineering for HPC, performance modeling and prediction, impacts of programming models and languages on productivity and efficiency, information visualization, and quantum chemistry. Recent work has focused on enabling data-intensive research in domains new to HPC, scaling diverse computational science codes and workflows to extreme-scale systems, deep hierarchies of parallelism, advanced filesystems, and architectural innovations in processors and interconnects.

Current Projects

  • Bridges: A uniquely capable data-intensive HPC system designed to empower new research communities, bring desktop convenience to HPC, expand campus access, and help researchers facing challenges in Big Data to work more intuitively. Called Bridges, the new system will consist of tiered, large-shared-memory resources with nodes having 12TB, 3TB, and 128GB each, dedicated nodes for database, web, and data transfer, high-performance shared and distributed data storage, Hadoop acceleration, powerful new CPUs and GPUs, and a new, uniquely powerful interconnect. Bridges will feature persistent database and web services to support gateways, collaboration, and new levels of access to data repositories. Bridges will also support a high degree of interactivity, gateways and tools for gateway-building, a very flexible user environment including widely-used software such as R, Java, Python, and MATLAB, and virtualization for hosting application-specific environments, enhancing reproducibility, and interoperating with clouds. Bridges will be a resource on XSEDE, NSF's Extreme Science and Engineering Discovery Environment, and will connect with other computational resources, data resources, and scientific instruments.
  • Data Exacell (DXC): A research pilot project to create, deploy, and test software and hardware building blocks to enable data analytics in scientific research. The DXC couples analytic resources with innovative storage to allow communities that traditionally have not used HPC to create valuable new applications. Pilot applications in data-intensive research areas such as genomics, radio astronomy, the digital humanities, biological imaging, and workflow management are being used to motivate, test, demonstrate, and improve the DXC building blocks including, for example, extensions to the SLASH2 filesystem, development of new tools for efficient data transfers and leveraging SDN, and enabling sophisticated, distributed software architectures for novel research domains through integration of database, web, and analytic technologies.
  • Center for Causal Discovery (CCD): An NIH BD2K Center of Excellence for Big Data Computing, the CCD aims to develop highly efficient causal discovery algorithms that can be practically applied to very large biomedical datasetsConduct projects addressing three distinct biomedical questions (cancer driver mutations, lung fibrosis, brain causome) as a vehicle for algorithm development and optimization.
  • Deciphering Cellular Signaling Systems by Deep Mining a Comprehensive Genomic Compendium: In this project led by Xinghua Lu (Univ. of Pittsburgh DBMI), we aim to reveal major cellular signals that regulate gene expression under physiological and pathological conditions and to infer the organization of signals in the human cellular signal transduction system (CSTS). Combining the identified signals with genomic alteration data and drug response data, we aim to further identify pathways underlying disease such as cancers, to use the genomic data to predict drug sensitivity of cancer cell lines, and to predict patient clinical outcomes in a pathway-centered manner.
  • Pittsburgh Genome Resource Repository (PGRR): The Pittsburgh Genome Resource Repository provides data management and computing infrastructure to support use of national genome data resources for personalized medicine research. PGRR provides a mechanism for University of Pittsburgh investigators to access and use these datasets from a virtualized central location using common tools and platforms.
  • Enabling Productive, High-Performance Data Analytics: Sherlock, a YarcData Urika™ graph appliance with PSC-specific customizations, is the first system of it kind made available to the NSF research community. Sherlock is a massively multithreaded supercomputer built on Cray Threadstorm 4.0 processors which implement multiple, powerful features to support lightweight multithreading, latency hiding, and advanced memory interfaces with AMD HyperTransport-attached SeaStar2 interconnect chips to provide a flat, globally-addressable memory. Optimized RDF and SPARQL implementations provide ease of use for large-scale graph analytics, and the system is also programmable using C/C++ and threads.
  • Exploring the Potential of “Native Client” for Computational Science: This project tests the usability and affordability of a new form of cloud service for providing more cost effective computational resources for certain types of research computations. A usability component of the test will determine the ease with which applications can be ported to the NaCl programming model.

PSC Staff Directory

 

Reception Area (412) 268-4960
FAX numbers
 Reception
 Business Office

(412) 268-5832
(412) 268-1490
User Services Hotline (Pgh) (412) 268-6350

 

PSC Executive Management
Mike Levine This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Scientific Director
Ralph Roskies This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Scientific Director
David Moses This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5645 Executive Director
Bob Stock This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6351 Associate Director
PSC Staff
Adams, Andy This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5142 Network Engineer
Allar, Jared This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2956 Information Security Analyst
Anderson, Erica This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6663 Preaward And HR Manager
Angeletti, Rich This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6074 Senior Network Engineer
Begandy, Cheryl This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5129 Director Of EOT
Benninger, Kathy This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5128 Manager Of Networking Research
Benton, Vivian This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6355 Communications/Publications Project Mgr
Berger, Ed This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6481 Sr Systems Specialist
Blood, Philip This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-9329 Senior Computational Scientist
Brown, Janet This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Principal Project Director
Brown, Shawn This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Director Of Public Health
Budden, Robert This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-9984 Sr Grid Cluster Systems Developer
Chiacchia, Ken This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5869 Senior Science Writer
Costa, Rick This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Staff Computational Science Consultant
Cubbison, Burt This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2846 Software Engineer
Cunningham, Steve This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6174 Senior Network Operations Engineer
Czech, Jacob This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-1782 Senior Scientific Research Programmer
Deems, Steve This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7618 Allocations Coordinator
Depasse, Jay This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6340 Sr. Computational Public Health Specialist
Dittrich, Markus This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-1688 Director Of Biomedical Applications Group
Filus, Shane This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Information Security Engineer
Gill, Bryon This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-9915 Advanced Computing Systems Specialist
Gomez, Roberto This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6885 Senior Computational Science Consultant
Goodwin, Ken This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7666 Director Of Networking
Hackworth, Ken This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7081 User Relations Coordinator
Haidari, Leila This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2461 Public Health App Specialist
Hanna, Ed This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7649 Coordinator of DIRS
Hood, Greg This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Senior Computer Scientist
Ishwad, Pallavi This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2676 Education Program Director
Jana, Anirban This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6885 Senior Computational Scientist
Jarzynka, Lucille This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6802 Administrative Analyst
Johanson, Brian This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7490 High Performance Computing System Administrator  
Kapcin, Dave This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5640 Director of Finance and Administration
Kar, Anjana This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Senior Storage Systems Specialist
Kasdorf, Jim This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7954 Director Of Special Projects
Laghaei, Rozita This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Research Scientist
Lambert, Michael This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7037 Gigapop Manager
Layman, Lynn This email address is being protected from spambots. You need JavaScript enabled to view it.   Economic Dev & Strategic Relationships
Learn, Bryan This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2210 Network Programmer
Leonard, Jim This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Sr. Public Health Applications Developer
Light, Robert This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6081 Senior Systems Software Engineer
Litzinger, Susan This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 File Systems Administrator
Madrid, Marcela This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5135 Senior Computational Scientist
Maiden, Tom This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5004 User Support and Outreach Coordinator
Marsteller, Jim This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5184 Chief Information Security Officer
McGinnis, Laura This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5642 Manager Of EOT
Nardozzi, Ray This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-3196 Procurement and Facilities Manager
Nicholas, Hugh This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5130 Senior Computational Scientist
Nigra, Deb This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2999 Sr Computational Science Consultant
Nystrom, Nick This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Director Of Strategic Applications
O'Neal, David This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Sr. Scientific Specialist
Perrone, Clint This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6132 Sr Systems Specialist
Rapier, Chris This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-1783 Senior Research Programmer
Raymond, Rich This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5133 User Services Manager
Robinson, Nate This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-9251 Network Engineer
Ropelewski, Alex This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7821 Senior Bioinformatics Specialist
Sanielevici, Sergiu This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Director Scientific App & User Support
Scibek, Robin This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-1326 Communications And Marketing Project Mgr
Scott, Ray This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Director Systems And Operations
Simmel, Derek This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-1035 Grid Computing Specialist
Sudac, Pat This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7137 Administrative Coordinator
Urbanic, John This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7861 Parallel Computing Specialist
Underwood, Richard This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2401 High Perf Computing System Administrator
Wang, Yang This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2795 Senior Computational Scientist
Webb, Bryan This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-5134 Systems and Facilities Administrator
Welling, Joel This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6352 Sr Scientific Specialist
Wetzel, Art This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-3912 Principal Computer Scientist
Williams, Shandra This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-7141 Manager of Multimedia Projects
Wozniak, Ed This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6198 High Perf Computing System Administrator
Yanovich, Jared This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-4960 Sr Advanced Computing Systems Developer
Zenkov, Eli This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-2461 Public Health Applications Developer
Zhang, Zhihui This email address is being protected from spambots. You need JavaScript enabled to view it. (412) 268-6972 Sr Advanced Sys Data Management Specialist

 

Public Health Administration

 

Shawn T. Brown, Director
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-4635

 

 

 

Jay DePasse, Senior Computational Public Health Specialist
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-3640

 

 

Leila Haidari, Public Health Applications Specialist
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-2461

 

 

Nathan Stone, Modeling & Project Management
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Phone: 412-268-4367

 

 

Eli Zenkov, Public Health Applications Developer
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Phone: 412-268-2461

Special Projects

James Kasdorf, Director
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-7954

 

 

Janet Brown, Principal Project Director
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-4960

 

 

 

H. Lynn Layman, Economic Development and Strategic Relationships Liaison
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-4960

 

Education, Outreach & Training

Cheryl Begandy, Director
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412 - 268-5129

 

 

Vivian Benton, Communications & Publications Project Manager
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412 - 268-6355

 

 

Ken Chiacchia, Senior Science Writer
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-5869

 

 

Robin Flaus, Communications and Marketing Project Manager
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412 - 268-1326

 

 

Pallavi Ishwad, Education Program Director
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Phone: 412-268-4960

 

 

Laura McGinnis, Manager of EOT
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412 - 268-5642

 

 

Robin Scibek, Communications and Marketing Project Manager
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412 - 268-1326

 

 

Shandra Williams, Manager of Multimedia Projects
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: 412-268-7141