HMMER
HMMER is a software suite for making and using Hidden Markov Models (HMMs) of biological sequences.
Installed on the Opteron Cluster.
Opteron cluster Version 2.3.2
It is convenient to use /biomed/lib/examples/.login.fixed for this and other sequence analysis packages.
Nine programs are available in /biomed/bin, as listed below. The links for each will take you to the appropriate man page.
- hmmalign, aligns sequences to an HMM profile.
- hmmbuild,
build a hidden Markov model from an alignment.
Example job - hmmcalibrate, calibrate HMM search statistics.
- hmmconvert, convert between profile HMM file formats.
- hmmemit, generate sequences from a profile HMM.
- hmmfetch, retrieve specific HMM from an HMM database.
- hmmindex, create SSI index for an HMM database.
- hmmpfam, search one or more sequences against HMM database.
- hmmsearch, search a sequence database with a profile HMM.
Or, see the general man page for hmmer.
Short descriptions, arguments and switches for the nine programs are displayed by typing:
/biomed/bin/program-name -h
HMMER Documentation:
- HMMER web site.
- User Guide for version 2.3.2 (pdf)
- Release notes for version 2.3.2
- User's Guide for HMMER, version 1.8.
See also:
- Other Nucleic Acid and Protein Sequence Analysis software installed at the PSC.